1. We all know about the germs that are recycled -- along with the air -- in a crowded airplane cabin. So keep your time on the plane as short as possible by booking flights early in the morning when you're least likely to be delayed. And travel on Monday (the day with the least crowded flights) rather than Thursday (the day with the biggest crowds).
2. Don't use the airline's blankets or pillows unless they come in a sealed bag. These items are not always washed between flights and can therefore be rife with the germs of the gent who drooled on the pillow an hour ago.
3. On long flights, get up and move around every hour or two to avoid cramped muscles and reduced circulation.
4. Hydrate, hydrate, hydrate!

In the Car

1. If you are preparing for a long trip, have a tune-up -- check the oil, tire pressure, etc. -- before you leave, and make sure you have emergency equipment, including flares, in your trunk.
2. Take a break from driving if you feel tired or sleepy.
3. Always lock your doors while you are driving and keep windows rolled up far enough so that no one can reach in while you are stopped at a traffic light.
4. Never leave the car unlocked and never leave the keys in the ignition -- even if you are just stopping for a moment.

With Children

1. If your child needs to use a car seat or booster seat, make sure you know how to install it correctly and always use it. (The American Academy of Pediatrics has a thorough online guide to help you.)
2. Bring along items to help child-proof your hotel room (or Grandma's house, if you're visiting relatives).
3. Young children have sensitive skin, so remember to slather them with sunscreen and put on a hat if you'll be outdoors.
4. Dress your child in bright, easy-to-recognize clothing and always carry a current photo in case you are separated.
5. Carry a first aid kit, that includes items such as antibiotic ointment, band aids, and Tylenol.

No matter where you are, always carry an alcohol-based hand sanitizer (like Purell) or cleansing wipes with you to use when soap and water aren't available.